NIHR Alder Hey Clinical Research Facility

NIHR Alder Hey Clinical Research Facility

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The NIHR Alder Hey Clinical Research Facility (CRF) provides a state-of-the-art and dedicated environment for patients, healthcare professionals, and academic and commercial partners to deliver leading edge research, placing Alder Hey at the forefront of improving the health and well-being of children and young people. It is the first ever facility of its kind in Merseyside and Cheshire.

In April 2017, the CRF received a substantial grant from the National Institute of Health Research (NIHR), enabling Alder Hey to further pioneer research to benefit children and young people.

The facility is staffed by an expert team of paediatric research delivery staff including research nurses, doctors (including those with specialist clinical pharmacology knowledge), clinical trial pharmacists, research physiotherapist, research play specialist and clinical trial coordinators. This enables the CRF to safely deliver complex research studies of new medications and interventions, including those requiring inpatient overnight care.

The facility is fully equipped and purpose built to carry out experimental medicine and early phase research studies. The child friendly environment of the facility enhances the experience of all those involved in research and helps encourage greater participation.

Studies conducted on the CRF are done so to strict Good Clinical Practice (GCP) standards. Sitting in the heart of Alder Hey Children’s Hospital, it is located close to critical care, medical inpatient facilities and supported by clinical support services. This means Alder Hey is providing the highest possible quality environment for safety, clinical and research governance.

Research Themes

Research taking place within the CRF covers all specialties within the hospital, however priority areas include four Experimental Themes and three Experimental Clusters, each led by Theme Leads as detailed below:

Experimental Themes

  • Inflammation – Prof Christian Hedrich
  • Infection – Prof Paul McNamara
  • Oncology – Dr Lisa Howell
  • Neurosciences – Prof Conor Mallucci

Experimental Clusters

  • Clinical Pharmacology and Dose optimization – Dr Dan Hawcutt
  • Formulations – Prof Matthew Peak
  • Innovation in Devices - Mr Iain Hennessey
Research Collaborations

The CRF team provides an outreach role, working with clinical teams in Paediatric Intensive Care, Oncology, A&E and the Neonatal Intensive Care Unit at Liverpool Women’s Hospital

In addition we work in collaboration with the team at the Royal Liverpool and Broadgreen University Hospital NHS Trust Clinical Research Unit (RLBUHT CRU) to offer a “life-course” platform for research in the city of Liverpool and across the region.

Importantly the CRF works in partnership with the academic sector, including the Faculties of Health & Life Sciences and Science & Engineering at the University of Liverpool; School of Pharmacy & Biomolecular Sciences at Liverpool John Moores University and the School of Pharmacy & Biomedical Sciences at the University of Central Lancashire to design and deliver research studies.

For more details, please contact:
Gaurika Kapoor, NIHR Alder Hey Operations Manager

Meet the Team

Professor Michael Beresford - Director

Professor Matthew Peak - Co-Director

Gaurika Kapoor - Operational Manager

Dr Dan Hawcutt – Clinical lead

Jacqui Tahari – Research Nurse Manager

Rebecca Donegan – Research Nurse

Hannah Leyland – Research Nurse

Dianne Lea – Research Nurse

Jackie Lyall – Research Nurse

Fiona Wilson – Research Nurse

Jackie Glover – Research Play Specialist

Udeme Ohia – Clinical trials Pharmacist

Nadia Ismail – Data Assistant

Aiste Adomaviciene – Neuromuscular trial coordinator

Rebecca Hamilton-Cook -  Industry Manager

Lucy Cooper - Quality Assurance & Research Governance Lead

Clinical Research Facility Service Evaluation

Notice for NIHR studies

Are you publishing following a study conducted at the Alder Hey CRF? Please use the following statement as this is required by the NIHR:

This is a summary of independent research funded by [name of research funder] and carried out at the National Institute for Health Research (NIHR) Alder Hey Clinical Research Facility. The views expressed are those of the author(s) and not necessarily those of the [name of research funder], NHS, the NIHR or the Department of Health.

To view our PPIE strategy, please click here.

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